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Indirect hyperbilirubinemia has occurred frequently during treatment with CRIXIVAN and has infrequently been associated with increases in serum transaminasessee also ADVERSE REACTIONSClinical Trials and Post-Marketing ExperienceIt is not known whether CRIXIVAN will exacerbate the physiologic hyperbilirubinemia seen in neonatesSee Pregnancy

Patients should be advised to avoid doing things that can spread HIV-1 infection to others.

If you miss a dose by less than 2 hourstake the missed dose as soon as you remember itHoweverif you miss a dose by more than 2 hoursskip the missed dose and continue your regular dosing scheduleDo not take a double dose to make up for a missed one.

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women receiving indinavir with hormonal contraceptives should report any breakthrough bleeding or other adverse effects.