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Patients with vitamin D-resistant ricketsfamilial hypophosphataemiawho are being treated with Rocaltrol must continue their oral phosphate therapyHoweverpossible stimulation of intestinal absorption of phosphate by Rocaltrol should be taken into account since this effect may modify the need for phosphate supplementation.

Hypersensitivity reactionspruritusrashurticariaand very rarely severe erythematous skin disordersmay occur in susceptible individualsOne case of erythema multiforme and one case of allergic reactionswelling of lips and hives all over the bodywere confirmed by rechallenge.

The treatment of acute accidental overdosage of Rocaltrolcalcitriolshould consist of general supportive measuresIf drug ingestion is discovered within a relatively short timeinduction of emesis or gastric lavage may be of benefit in preventing further absorptionIf the drug Buy stromectol ireland has passed through the stomachthe administration of mineral oil may promote its fecal eliminationSerial serum electrolyte determinationsespecially calciumrate of urinary calcium excretionand assessment of electrocardiographic abnormalities due to hypercalcemia should be obtainedSuch monitoring is critical in patients receiving digitalisDiscontinuation of supplemental calcium and a low-calcium diet are also indicated in accidental overdosageDue to the relatively short duration of the pharmacological action of calcitriolfurther measures are probably unnecessaryShouldhoweverpersistent and markedly elevated serum calcium levels occurthere are a variety of therapeutic alternatives which may be considereddepending on the patient’s underlying condition.

Rocaltrolcalcitriolis indicated in the management of hypocalcemia and the resultant metabolic bone disease in patients undergoing chronic renal dialysisIn these patientsRocaltrolcalcitrioladministration enhances calcium absorptionreduces serum alkaline phosphatase levelsand may reduce elevated parathyroid hormone levels and the histological manifestations of osteitis fibrosa cystica and defective mineralization.

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can rocaltrol be taken for nursing mothers or during breastfeeding.