Inform patients and caregivers clozaril is available only through a restricted program called the clozaril rems program designed to ensure the required blood monitoring, in order to reduce the risk of developing severe neutropenia.

Information about Clozaril.

Prescribers are encouraged to keep a record of all patientsblood results and to take any steps necessary to prevent the patient being accidentally rechallenged in the future.

Since Clozaril may be associated with thromboembolismimmobilisation of patients should be avoided.

Patients with rare hereditary problems of galactose intolerancethe Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.

Clozaril is indicated in treatment-resistant schizophrenic patients and in schizophrenia patients who have severeuntreatable neurological adverse reactions to other antipsychotic agentsincluding atypical antipsychotics.

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reduce clozaril dose based on clinical response.