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Frequency not reportedHypersensitivityallergic reactionsanaphylactic reactionsRef]

COUMADIN has no Confido tab price direct effect on an established thrombusnor does it reverse ischemic tissue damageOnce a thrombus has occurredhoweverthe goals of anticoagulant treatment are to prevent further extension of the formed clot and to prevent secondary thromboembolic complications that may result in serious and possibly fatal sequelae.

COUMADIN has a narrow therapeutic rangeindexand its action may be affected by factors such as other drugs and dietary vitamin KThereforeanticoagulation must be carefully monitored during COUMADIN therapyDetermine the INR daily after the administration of the initial dose until INR results stabilize in the therapeutic rangeAfter stabilizationmaintain dosing within the therapeutic range by performing periodic INRsThe frequency of performing INR should be based on the clinical situation but generally acceptable intervals for INR determinations are 1 to 4 weeksPerform additional INR tests when other warfarin products are interchanged with COUMADINas well as whenever other medications are initiateddiscontinuedor taken irregularlyHeparina common concomitant drugincreases the INRsee Conversion From Other Anticoagulants and DRUG INTERACTIONS

More frequent INR monitoring should be performed when starting or stopping botanicals.

Frequency not reportedHypersensitivityallergic reactionsanaphylactic reactionsRef]

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