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Ezetimibe and simvastatin can cause the breakdown of muscle tissuewhich can lead to kidney failureThis happens more often in womenin older adultsor in people who have kidney disease or poorly controlled hypothyroidismunderactive thyroid

In additionan apparent hypersensitivity syndrome has been reported rarely that has included one or more of the following featuresanaphylaxisangioedemalupus erythematous-like syndromepolymyalgia rheumaticadermatomyositisvasculitispurpurathrombocytopenialeukopeniahemolytic anemiapositive ANAESR increaseeosinophiliaarthritisarthralgiaurticariaastheniaphotosensitivityfeverchillsflushingmalaisedyspneatoxic epidermal necrolysiserythema multiformeincluding Stevens-Johnson syndrome.

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor instructs you otherwiseGrapefruit can increase the amount of this medication in your bloodstreamConsult your doctor or pharmacist for more details.

Gastrointestinal disordersabdominal painconstipationdyspepsiaflatulencegastritis;

Generic Nameezetimibe and simvastatinez ET i mibe and SIM va stat inBrand NamesVytorin.

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